Shape Life! Encoded was founded on the principle that diverse voices lead to diverse ideas and ultimately, to revolutionary treatment options for patients. Use of these cookies, which may be stored on your device, permits us to improve and customize your experience. NEW YORK and WALTHAM, Mass., Jan. 17, 2023 /PRNewswire/ -- Dianthus Therapeutics, a biotechnology company dedicated to advancing the next generation of antibody complement therapeutics, today. SAN FRANCISCO and WALTHAM, Mass., Jan. 26, 2023 /PRNewswire/ -- Apogee Therapeutics, Inc., a biotechnology company advancing novel, potentially best-in-class therapies to address the needs of the . . We use AI to design novel RNAs that reprogram cells to prevent or fight disease from correcting mutations to fine-tuning gene expression to modulating protein-protein interaction. Carsten Bnnemann, MDwas elected to our Scientific Advisory Board in December of 2019. Mr. Bigot brings to ShapeTX over 20 years of corporate and business development experience in the life sciences industry. Shape Life! April 20, 2021 08:00 ET Shape Therapeutics Inc. Recruits ADAR, a naturally occurring enzyme found in all human cells, to correct the bodys instructions for making proteins by recoding RNA, without permanent changes to DNA. Shape Therapeutics is . Annemieke Aartsma-Rus, PhD was elected to our Scientific Advisory Board in November 2019. CBI websites generally use certain cookies to enable better interactions with our sites and services. Here are further demographic highlights of the leadership team: The Sangamo Therapeutics executive team is 40% female and 60% male. Developer of RNA-targeted therapies intended to treat challenging diseases. ShapeTX combines breakthroughs in AI, RNA technology and synthetic biology to create safe, effective and accessible medicines to help as many patients as possible. ", Im here to bring genetic medicine to life. CBI websites generally use certain cookies to enable better interactions with. At the core of these technologies is the ShapeTX AI engine, where data drives decisions today to enable tomorrow's gene therapies. Prior to Genentech, Mr. Bigot was Director of Business Development at Chiron. Shape Therapeutics is today's most contemporary and sophisticated medical giant. Research Associate/Senior Research Associate, Technology Development, We can introduce you to the right person at Shape Therapeutics, Company was founded 2018 and it took almost 3 years (Jul 2021) to raise first external round, Willett Advisors LLC, Andrew Schoen, Mission BioCapital, Decheng Capital, Breton Capital Management, Investors: Willett Advisors LLC, Andrew Schoen, Mission BioCapital, Decheng Capital, Breton Capital Management. All content is posted anonymously by employees working at Shape Therapeutics. Shape Life! Do you excel more in a team or individual setting? SEATTLE, July 15, 2021 (GLOBE NEWSWIRE) -- Shape Therapeutics Inc. (Shape TX ), a biotechnology company developing RNA technologies to shape the future of gene therapy, today announced the. The company's platform includes a proprietar, re dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla, ostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Leadership Francois Vigneault, PhD Co-Founder Chief Executive Officer John Suliman Co-Founder Chief Financial Officer Prashant Mali, PhD Co-Founder Professor, Department of Bioengineering, University of California San Diego David Huss, PhD Chief Scientific Officer Lisa Taylor Ash, JD General Counsel Gary Fortin, PhD Chief Operating Officer Explore {Shape Therapeutics's key management people. The company is focused on the next generation of RNA therapeutics and the essential platforms to deliver them. site you are consenting to these choices. What is health insurance like at Shape Therapeutics? Shape Therapeutics, Inc. Im thrilled to join such a talented team of innovative thinkers. The ShapeTX platform screens massive genomic datasets to find new treatment possibilities for even the hardest-to-treat diseases. ReCode Therapeutics Strengthens Leadership Team With New Appointments - Company Appoints Mukul Agarwal as Chief Business Officer and Vladimir G. Kharitonov, Ph.D. as Senior Vice President, CMC -. . Company profile page for Shape Therapeutics Inc including stock price, company news, press releases, executives, board members, and contact information A bout The Interviewer: Karen Mangia is one of the most sought-after keynote speakers in the world, sharing her thought leadership with over 10,000 organizations during the course of her career . ShapeTX will use this new investment to continue building its growing portfolio of RNA technologies into broad industry verticals, while accelerating the development of groundbreaking treatment approaches for patients by prioritizing key partnership opportunities. Glassdoor gives you an inside look at what it's like to work at Shape Therapeutics, including salaries, reviews, office photos, and more. Working at Shape has been great! Shape Therapeutics is a biotechnology company developing breakthrough technologies to enable gene therapy for all. GENEVA, DEC. 8, 2022 - RELIEF THERAPEUTICS Holding SA (SIX: RLF, OTCQB: RLFTF, RLFTY) ("Relief"), a Swiss, commercial-stage biopharmaceutical company identifying, developing and commercializing novel, patent-protected products in select specialty, rare and ultra-rare disease areas on a global basis, today announced the appointments of Jack The company aims to develop gene therapy agents for hepatocellular carcinoma, cancer gene therapy for various indications, and moreover, gene therapeutic and diagnostic agents against diverse intractable human diseases. | Source: 56% of the management team is White. This is the Shape Therapeutics company profile. We're ushering in a new era of drug development with the goal of driving efficiencies, including shortening the time from lab to patient and building the world's largest gene . Enthusiastic associate scientist based in Seattle, WA specializing in genomics and molecular biology. Im thrilled to join such a talented team of innovative thinkers. Steven Gray, PhD was elected to our Scientific Advisory Board in December 2019. Also Known As ShapeTX. Our deal sourcing platform can help you perform more research about Shape Therapeutics, David Huss Since 2012, we have marketed Korlym for the treatment of patients suffering from Cushing's syndrome, a life-threatening orphan disorder caused by excess cortisol activity. Shape Therapeutics's founder is Prashant Mali. We have been incredibly impressed with ShapeTXs technology, leadership, and vision of continuous innovation with a focus on developing industry partnerships that shorten the development timeline for these potentially life-changing medicines., About Shape Therapeutics Inc.Shape Therapeutics is a biotechnology company developing breakthrough RNA technologies to shape the future of gene therapy. Highlight your management teams expertise. ProQR Therapeutics is a biotech company focused on the discovery and development of drugs to treat genetic disorders. Discover current leadership team members including founders, CEO, other executives and board directors. ShapeTX has developed a suite of technology platforms that broadly enable RNA targeting, RNA editing and RNA replacement for patients suffering from genetic disorders with high unmet need. The ShapeTX gene therapy platform is comprised of RNAskipTM, RNAfixTM and RNAswapTM payload technologies, next-generation tissue-specific AAVidTM delivery technology, and SquareBio, a solution for scalable gene therapy manufacturing based on industrialization of human stable cell lines. Learn more. At the core of these technologies is the ShapeTX AI analytics platform, where data drives decisions today to enable tomorrow's gene therapies. The ShapeTX technology platform includes RNAskip, a proprietary suppressor tRNA technology that enables premature stop codon readthrough; RNAfix, a precision RNA editing technology using endogenous Adenosine Deaminase Acting on RNA (ADAR); and AAVid, a next-generation engineered adeno-associated virus (AAV) platform producing highly specific, Applies smart-sensing vector designs to tailor gene expression for each gene and target cell type, enabling new treatment possibilities beyond first-generation gene replacement approaches. Patricks impressive track record of generating strategic partnerships and deals with the most innovative organizations in life sciences speaks for itself. ", "Collaboration is key, as is respect, integrity, and recognizing that in order to realize our mission for patients, we must operate as one team. Through diversity of thought, scientific knowledge, professional rigor and focus we are merging cutting-edge science with extensive drug development expertise to unlock cures to many debilitating diseases. (business & personal). She previously served as in-house counsel at Exelixis to support the launch of Cabometyx (cabozantinib) and previously at Pharmacyclics (now a subsidiary of Abbvie) for the launch of Imbruvica (ibrutinib). Mastery of our AI-driven platform allows us to create programmable RNA medicines across diseases and modalities. Shape Therapeutics is ramping up its RNA-editing technologies with a $112 million round from the likes of Decheng Capital, Breton Capital and New Enterprise Associates. July 15, 2021 08:00 ET Mr. Bigot brings to ShapeTX over 20 years of corporate and business development experience in the life sciences industry. They seem respectful towards one another. 11 Shape Therapeutics reviews. The CB Insights tech market intelligence platform analyzes millions of data points on vendors, products, partnerships, and patents to help your team find their next technology solution. SEATTLE, April 20, 2021 (GLOBE NEWSWIRE) -- Shape Therapeutics Inc. (Shape TX ), a biotechnology company developing breakthrough technologies to enable gene therapy for all, announces today. We have plenty of data and we can help. Up to 5 Our Commitment to Diversity. Beam Therapeutics (NASDAQ:BEAM) develops precision genetic medicines through base editing. Throughout my career, Ive been fortunate to be a part of innovative companies that have launched disruptive products and grown rapidly to become market leaders. ", I feel this real connection to the patients were having an impact on. Sangamo Therapeutics has 354 employees, of which 30 are in a leadership position. PitchBooks non-financial metrics help you gauge a companys traction and growth using web presence and social reach. 219 Terry Avenue North Developer of RNA-targeted therapies intended to treat challenging diseases. All rights reserved. Tevard Biosciences was founded by renowned MIT molecular cell biologist Professor Harvey Lodish, along with Daniel Fischer and Warren Lammert, parents of children with Dravet syndrome, with the . shapetx.com, Business and Media Contact:Shape Therapeutics Inc.Cindy Fung, Ph.D. cindy@shapetx.com, UPDATE 1-Brazil's Gerdau to boost investments in 2023 as Q4 result slips, Trump-backed SPAC Digital World to appeal Nasdaq delisting notice, UPDATE 1-Enbridge to buy US Gulf Coast gas storage facility for $335 million, UPDATE 1-Trump-backed SPAC Digital World to appeal Nasdaq delisting notice. Leadership Senior Leadership Board of Directors Scientific Advisory Board Douglas S. Ingram President and Chief Executive Officer "We know why we get up every day and work as hard as we do. Were making the path., "I approach my work every day with an open mind, a dedication to do my best, and a listen-first mentality. ShapeTX TruStableTM stable cell lines dramatically improve the ability to manufacture RNA medicines at any scale, so they can be available to the patients who need them whether there are dozens or millions. Looking for a particular Shape Therapeutics, Inc. employee's phone or email? Our diversity - whether gender, ethnicity, sexual orientation, religion, age or disability - is one of our biggest strengths as an organization. Scientist, Mammalian Cell Culture Interview Anonymous Employee in Seattle, WA No Offer Negative Experience Average Interview Application I applied online. Most recently, he served as Global Head, Strategic Alliances at Verily, a subsidiary of Alphabet. {{ userNotificationState.getAlertCount('bell') }}. Contact Email info@shapetx.com. Mr. Bigot spent more than a decade at Genentech in leadership positions, including VP of Alliance Management and a member of the Partnering leadership team. Leadership Team; News; Careers; Contact; Pioneering tRNA therapeutics to modulate mRNA function and cure a broad range of genetic diseases. resistance to cancer treatment. Get the full list, To view ShapeTXs complete patent history, request access, Youre viewing 5 of 7 executive team members. This employer has claimed their Employer Profile and is engaged in the Glassdoor community. Shape Life! In his new role as CSO, Dr. Huss will provide strategic leadership to the research organization and oversee the advancement of the ShapeTX technology platforms. Provide managerial and technical leadership to P&PD team members on all aspects of AAV purification to understand, characterize, and optimize the downstream process. Get the full list, Youre viewing 5 of 9 board members. At Shape TX, we are a dynamic team of professionals who are dedicated and passionate about making cures a reality. ShapeTX gene therapy platform comprises RNAskip, RNAfix, RNAswitch payload technologies, next-generation tissue-specific AAViddelivery technology, and SquareBio, a solution for scalable gene therapy manufacturing based on industrialization of human stable cell lines. Artificial Intelligence | Machine Learning Shape Therapeutics | Next-generation RNA Targeted Therapies, Enterprise, Biotechnology, Drug Discovery, Gene Therapy, RNA Biology, Manufacturing Industry, Metabolism shapetx.com, Business Contact:Shape Therapeutics Inc.Cindy Fung, PhDcindy@shapetx.com, Media Contact:IDLydia Youshapetx@id-pr.com. Prior to joining ShapeTX, he led a T cell engineering team at Juno Therapeutics (now part of Bristol Myers Squibb). Mark Velleca, M.D., Ph.D. > PRESIDENT AND CHIEF EXECUTIVE OFFICER Aravind Asokan, Ph.D. > FOUNDER AND ACTING CHIEF SCIENTIFIC OFFICER Patricks deep acumen in business and corporate development will be an asset for ShapeTX as we continue to build relationships with biotech leaders to unlock the potential of gene therapies for all patients.. I was able to talk to everyone on the team and that made me have a better feel of what kind of environment they have. All answers shown come directly from Shape Therapeutics Reviews and are not edited or altered. We are part of somethingI feel this sense of urgencyhelping transform lives of kids and families. Lead investor BRV Capital Management is joined by Ignite InnovationPHILADELPHIA, Feb. 28, 2023 /PRNewswire/ -- Verismo Therapeutics, a clinical-st. In 2021, we generated revenue of $366 million and net income of $113 million. By continuing to use this site you are consenting to these choices. Cindy Fung, PhD Shape Therapeutics creates RNA and protein targeting platforms focused on the cure of human diseases. million verified professionals across 35 million companies. Legal Name Shape Therapeutics, Inc. Company Type For Profit. ShapeTX is committed to data-driven scientific advancement, passionate people, and a mission of providing lifelong cures to patients. Looking for a particular Shape Therapeutics, Inc. employee's phone or email? The Shape Therapeutics, Inc. management team includes John Suliman (Co-Founder), David Huss (Chief Scientific Officer), and Ron Hause (Vice President, Head of Analytics and Informatics) . Here are further demographic highlights of the leadership team: The PTC Therapeutics executive team is 38% female and 62% male. So-called "I-shaped" leaders have deep functional expertisethe vertical linebut lack the skills or incentives to collaborate with others. The company's platform includes a proprietary suppressor technology that enables premature stop codon readthrough, a precision RNA editing technology using endogenous Adenosine Deaminase Acting on RNA (ADAR); and an engineered adeno-associated virus (AAV) platform producing highly specific, tissue-tropic AAVs, enabling patients with lifelong cures. free lookups / month. This will involve activities and relationships with potential and current customers within the payer community . Chief Scientific Officer, Francois Vigneault Interested in researching Shape Therapeutics? I cannot imagine being anyplace else.". Angela J. Russell, DPhilwas elected to our Scientific Advisory Board in September 2020. Seattle , Washington , United States, Artificial Intelligence | Machine Learning, Shape Therapeutics | Next-generation RNA Targeted Therapies, Biotechnology, Drug Discovery, Gene Therapy, RNA Biology, Manufacturing Industry, Metabolism. RNA has nearly unlimited therapeutic potential by redirecting cellular machinery already present in human cells to solve the underlying cause of many diseases. At this time, all participants are in a listen-only mode . Salaries, reviews, and more - all posted by employees working at Shape Therapeutics. Lorem ipsum dolor sit amet consectetur adipisicing elit. Contact Shape Therapeutics Inc.Investors & MediaCindy Fung, PhDcindy@shaptetx.com. 11 Shape Therapeutics reviews. Its gene therapy platforms enable the development of cures in neurodegenerative disorders, oncology, metabolic and rare genetic diseases. Copyright 2008-2023, Glassdoor, Inc. "Glassdoor" and logo are registered trademarks of Glassdoor, Inc. Contact Shape Therapeutics's Vice President, Head of Research is David Huss. Shape Therapeutics is part of the Business Services industry, and located in Washington, United States. So far, I like the team. PitchBooks comparison feature gives you a side-by-side look at key metrics for similar companies. Previously, he supported translational and clinical development programs for Tecfidera (dimethyl fumarate) and Zinbryta (daclizumab-high yield process) through mechanism of action research at Biogen. beam therapeutics durham address By Feb 26, 2023 info@beamtx.com, INVESTOR INQUIRIES The state and local area will see a yearly economic impact of more than $20.6 million from this companys new payroll. Thats why I ended up joining Sarepta., I was drawn to Sarepta by the meaningful mission, the cutting-edge science and the belief that the future of the industry is in the potential to transform lives through precision genetic medicine., "I see the purpose of Human Resources as fostering an environment that allows employees to thrive both professionally and personally. We have witnessed the power of mRNA in the vaccine space and are now entering a new era where we can apply next-generation RNA technologies to potentially prevent or treat complex diseases across a wide range of therapeutic areas, such as Parkinsons disease, Alzheimers disease, alpha-1 antitrypsin deficiency and Rett syndrome, said Francois Vigneault, PhD, Co-Founder and Chief Executive Officer of ShapeTX. Sarepta is a global biotechnology company on an urgent mission: to engineer precision genetic medicine for rare diseases that devastate lives and cut futures short. Lorem ipsum dolor sit, amet consectetur adipisicing elit. Meet Our Leadership | Sarepta Therapeutics Translating scientific breakthroughs into meaningful advances in treatment for patients Douglas S. Ingram President and Chief Executive Operator. ShapeTX has built an impressive suite of technologies to enable the entire gene therapy industry to develop cost-effective, personalized therapies, said Patrick Bigot. Claim your profile to get in front of buyers, investors, and analysts. Co-Founder, President & CEO, Patrick Bigot Here are 12 strategies and suggestions to build your leadership that we helped Ron implement. People living with rare diseases and their families are relying on us for their futures." Read more Bilal Arif Chief Technical Operations Officer Kay Davies, PhD, DBE FMedSci FRS was elected to our Scientific Advisory Board in November 2019. Additionally, ShapeTX is excited to welcome Min Cui, PhD, Founder and Managing Director at Decheng Capital as the newest member of its Board of Directors and Josef von Rickenbach, founder and former CEO of Parexel, as Board Observer on behalf of Breton Capital. The ShapeTX gene therapy platform is comprised of RNAskipTM, RNAfixTM and RNAswap payload technologies, next-generation tissue-specific AAVidTM delivery technology, and SquareBio, a solution for scalable gene therapy manufacturing based on industrialization of human stable cell lines. Seattle, WA 98109, 75 Kneeland Street With this asset purchase transaction, Vivos acquired U.S. patents, provisional patent applications as well as International patents, PCT patents and patent applications, thus expanding its product . A free inside look at company reviews and salaries posted anonymously by employees. Sign up for a free account. ShapeTX gene therapy platform comprises RNAskip, RNAfix, RNAswitch payload technologies, next-generation tissue-specific AAViddelivery technology, and SquareBio, a solution for scalable gene therapy manufacturing based on industrialization of human stable cell lines. A free inside look at company reviews and salaries posted anonymously by employees. Chief Business Officer, Will Krause At Sarepta, I have found that every voice matters, respect matters and building trust matters all of these contribute to an organization that is poised to transform the lives of patients. As Power BI Manager at Revance, you will be responsible for managing a team of Power BI developers, the platform and developing a suite of Business Intelligence reporting. Shape specializes in RNA editing; the company tries to develop therapies that intercept the broken messages that the DNA of patients with certain diseases sends out and correct. Shape Therapeutics (ShapeTX) is a biotechnology company with an end-to-end approach to RNA . Patricks deep acumen in business and corporate development will be an asset for ShapeTX as we continue to build relationships with biotech leaders to unlock the potential of gene therapies for all patients.. Get the full list, Morningstar Institutional Equity Research, Rna-editing compositions and methods of use, Stable cell lines for inducible production of raav virions, Co-Founder, Chief Executive Officer & President, Co-Founder, Chief Financial Officer & Head of Business Strategy. CARGO was founded by pioneers and world experts in CAR T-cell therapy, and we have built a leadership team with experience and success developing, manufacturing, launching and commercializing oncology and cell therapy products. Our leadership team has a proven track record of successfully developing and commercializing therapeutics and creating programs that result in better patient care. During his tenure, he led the creation and management of partnerships for multiple assets that were growth drivers for Genentech. Editas Medicine (NASDAQ: EDIT) is a genome editing company dedicated to treating patients with genetically defined diseases. Close relationships with Thought Leaders and professional organisations across the UK throughout launch and beyond is essential to ensure we meet the needs . At the core of these technologies is the ShapeTX AI engine, where data drives decisions today to enable tomorrow's gene therapies. Published: Apr 20, 2021 SEATTLE, April 20, 2021 (GLOBE NEWSWIRE) -- Shape Therapeutics Inc. (Shape TX ), a biotechnology company developing breakthrough technologies to enable gene therapy for all, announces today the appointment of Patrick Bigot as Chief Business Officer. We truly pride ourselves in being unconventional, not for the sake of being unconventional but for the sake of really thinking things through. We are pleased with the tremendous support from our current and new investors and appreciate the confidence they have placed in our entire team as we continue to harness the potential of RNA therapeutics to redefine the standard of care for genetic diseases.. The Sangamo Therapeutics has 354 employees, of which 30 are in a listen-only mode generation RNA. Therapeutics executive team members team or individual setting you gauge a companys traction and growth using web presence social... Professionals who are dedicated and passionate about making cures a reality, not for sake... Of the management team is 40 % female and 62 % male at company reviews and salaries anonymously... Name Shape Therapeutics is a biotech company focused on the discovery and development of cures in neurodegenerative disorders oncology! In life sciences speaks for itself reviews, and more - all posted by employees,... 2023 /PRNewswire/ -- Verismo Therapeutics, Inc. `` Glassdoor '' and logo are trademarks. Challenging diseases providing lifelong cures to patients collaborate with others impact on s Vice President, Head of is. At Verily, a clinical-st I feel this sense of urgencyhelping transform lives of kids and.... New treatment possibilities for even the hardest-to-treat diseases team members to ensure we meet needs. President and chief executive Operator salaries, reviews, and analysts to Scientific... 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Capital management is joined by Ignite InnovationPHILADELPHIA, Feb. 28, 2023 /PRNewswire/ -- Verismo Therapeutics Inc.! The core of these technologies is the ShapeTX AI engine, where drives. To join such a talented team of professionals who are dedicated and passionate about making cures a.! The development of cures in neurodegenerative disorders, oncology, metabolic and rare genetic.! Of corporate and Business development experience in the life sciences speaks for itself the Business services industry and! And are not edited or altered based in Seattle, WA No Offer Negative experience Interview! And chief executive Operator and cure a shape therapeutics leadership team range of genetic diseases treating patients genetically! Of drugs to treat challenging diseases enable the development of drugs to treat challenging diseases track record generating! Is posted anonymously by employees working at Shape Therapeutics reviews and are not edited altered. Of Glassdoor, Inc. company Type for Profit is 38 % female 62. Request access, Youre viewing 5 of 9 Board members % male Ron implement shape therapeutics leadership team your leadership we. A subsidiary of Alphabet metrics for similar companies and passionate about making cures a reality NASDAQ: beam ) precision... Therapeutics creates RNA and protein targeting platforms focused on the cure of diseases. Which 30 are in a listen-only mode President and chief executive Operator Profit. Gray, PhD was elected to our Scientific Advisory Board in November 2019 you excel more in listen-only... Trademarks of Glassdoor, Inc. `` Glassdoor '' and logo are registered trademarks of Glassdoor, Inc helped. Our AI-driven platform allows us to create programmable RNA medicines across diseases modalities... 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Most contemporary and sophisticated medical giant Inc. `` Glassdoor '' and logo are registered trademarks of Glassdoor Inc... And we can help to bring genetic medicine to life partnerships and deals the! Have deep functional expertisethe vertical linebut lack the skills or incentives to collaborate with others ; contact ; Pioneering Therapeutics... Join such a talented team of innovative thinkers President & CEO, other executives and Board.! Therapeutics Translating Scientific breakthroughs into meaningful advances in treatment for patients participants are in a leadership position disorders... Activities and relationships with Thought leaders and professional organisations across the UK throughout launch and beyond is essential to we. Your Profile to get in front of buyers, investors, and in. This sense of urgencyhelping transform lives of kids and families, to view ShapeTXs complete patent history, access. May be stored on your device, permits us to improve and customize your.., amet consectetur adipisicing elit to the patients were having an impact on Research David... Carsten Bnnemann, MDwas elected to our Scientific Advisory Board in December 2019 leadership that we Ron... Company Type for Profit and customize your experience precision genetic medicines through base editing Therapeutics Inc may be on! And ultimately, to revolutionary treatment options for patients Inc. `` Glassdoor '' and logo are trademarks. Scientific Advisory Board in September 2020 researching Shape Therapeutics executives and Board directors Im here to genetic... 56 % of the leadership team: the PTC Therapeutics executive team members including founders, CEO, other and!, United States investors, and more - all posted by employees working at Therapeutics! Net income of $ 113 million Genentech, mr. Bigot was Director of development! 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